Question

Why does the local and systemic absorption of topical anesthetics increase the risk of toxicity?

Answer 1

The risk of local and systemic absorption increases with higher concentrations of topical anesthesia and in the absence of vasoconstricting abilities.

Local and infiltration anesthetics can have local or systemic toxicity. Local adverse reactions include neurovascular manifestations such as sustained anesthesia , which can be irreversible. Vasoconstrictors are not present in anesthetics. High concentrations of topical anesthetics are used. Due to vasodilation of the area, topical anesthetics are quickly absorbed into the tissue and bloodstream. The risk of local and systemic absorption increases with higher concentrations of topical anesthesia and in the absence of vasoconstricting abilities.

A cautious injection technique may aid in the prevention of toxic reactions.

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