Question

Why does testosterone, a lipid-soluble signal ing molecule that crosses the membranes of all cells, affect only target cells? (A) Only target cells retain the appropriate genes regulated by testosterone. (B) Intracellular receptors for testosterone are present only in target cells. (C) Only target cells possess the cytosolic enzymes that transduce the signal from testosterone to adenylyl cyclase. (D) Only in target cells is testosterone able to initiate the phosphorylation cascade leading to activated transcription factor.

Answer 1

Testosterone is a lipid-soluble signaling molecule that crosses the membranes of all cells and affects only target cells because intracellular receptors for testosterone are present only in target cells.

Testosterone is the male sex or gamete hormone which is made in the male testicles. Testosterone hormone levels are very important to normal male sexual development and its functions.

Therefore, testosterone signals can be translated directly to changes in gene expression, and this hormone activates kinases that regulate processes required to maintain spermatogenesis as this is lipid-soluble, so it does not require any molecular event for transmission. They can dissolve in the body and can travel through the cell membranes easily.

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