A systematic review and meta-analysis of efficacy and safety of negative pressure wound therapy in the treatment of diabetic foo

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1 year ago

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t ulcer

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andrew11 [14] · Answer 1 · 2024-04-12T05:28:00+03:00

Diabetes complications have grown in recent years as the prevalence of the disease has increased.

A systematic review and meta-analysis of efficacy and safety of negative pressure:

(1). A frequent diabetes consequence known as diabetic foot (DF) is hyperglycemia, which results in peripheral nerve and vascular lesions, dry and itchy skin on the feet, and eventually leads to ulcers that take a long time to heal and reduce patients' quality of life
(2). Numerous novel techniques have been gradually implemented in the treatment of wounds as new medical therapies have emerged, guided by cytohistology and biochemistry.
(3). One such technique is known as negative pressure wound therapy (NPWT), which can be used to treat superficial wounds and drain deep wounds. It can completely remove the necrotic tissue and wound secretions, stimulate the production of granulation tissue, lower bacterial infection levels, and accelerate wound healing
(4). In essence, NPWT is a mechanical system that uses a tube to attach to a suction device to produce a sub-atmospheric pressure between the wound and the outside to clear exudate and quicken healing.
(5). Despite the fact that NPWT is generally acknowledged to be successful, there are significant variations in clinical literature reports, and there is a dearth of quantitative analysis of study data.

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