Answer:
The three methods are: 1) Using H-Ras- SREBP- 2 Fusion proteins, the NH2 segment can be released by two sequentia
Explanation:
Sterol regulatory element binding proteins (SREBPs) are transcription factors attached to the endoplasmic reticulum. The NH2-segment, which activates transcription, is connected to membranes by a hairpin anchor formed by two transmembrane sequences and a short lumenal loop. Using H-Ras–SREBP-2 fusion proteins, we show that the NH2-segment is released from membranes by two sequential cleavages. The first, regulated by sterols, occurs in the lumenal loop. The second, not regulated by sterols, occurs within the first transmembrane domain. The liberated NH2-segment enters the nucleus and activates genes controlling cholesterol synthesis and uptake. Certain mutant Chinese hamster ovary cells are auxotrophic for cholesterol because they fail to carry out the second cleavage; the NH2-segment remains membrane-bound and transcription is not activated.
Answer:
The correct word to be fill in the blank is 'energy.'
Explanation:
Secondary active transport is a type of active transport, which involves transport of molecules or ions across the membrane against their concentration gradient by using energy.
In secondary active transport, energy is provided by electrochemical gradient. It involves transport of two molecules or ions (either in same or opposite direction) and required energy is generated due to difference in electrochemical gradient formed by pumping or ions across the cells.
An example of secondary transport is transport of potassium ions by K+/H+ exchanger that transports hydrogen ions and potassium ions in opposite direction. It uses energy from proton motive force (generated by transport of hydrogen ions or protons) to transport potassium ions.
Thus, the correct answer is 'energy.'
Answer:
Chlorpromazine treats mental disorders, severe behavior disorders, severe hiccups, severe nausea and vomiting, and certain types of porphyria. Also used before and after surgery to relieve anxiety. Belongs to a class of drugs called phenothiazines.
The answer is C i believe
