"Mathew Meselson and Franklin Stahl performed classic experiments that supported semiconservative nature of DNA replication in 1985."
A band of hybrid 14N and 15N DNA was produced as a result of the DNA's initial duplication in a 14N medium. The conservative replication mode was so abandoned. "Based on their observations and experimental results, Meselson and Stahl concluded that DNA molecules can replicate semi-conservatively."
One original DNA serves as a template for the production of two DNA copies during conservative replication. One of these two is made entirely of fresh DNA, while the other is made of strands from old DNA. In semiconservative replication, the parent strand is used to make two copies of the DNA, each of which contains one original strand and the other new strand.
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