Some substances that were not initially filtered in the glomerulus, but must be eliminated from the blood, become a component of urine through the process of urine formation.
Urine: A liquid excrement consisting of water, salts, and urea, which is made in the kidneys then released through the urethra.
The process of urine formation involves 3 major steps:
Filtration:- Blood enters the afferent arteriole during filtration, flowing into the glomerulus where filterable blood components—such as water and nitrogenous waste—move toward the interior of the glomerulus and nonfilterable blood components—such as cells and serum albumins—exit via the efferent arteriole.
Reabsorption: During this, ions and molecules will be returned to the bloodstream. As the fluid's osmolarity (ion concentration) fluctuates, water and ions are eliminated as it moves through the proximal/distal convoluted tubules, the loop of Henle, and the collecting duct.
The process of secretion involves the removal of various substances from the blood into the collecting duct, including hydrogen ions, creatinine, and medications. Urine, the final result of all these procedures, is essentially a collection of chemicals that have not undergone tubular or glomerular reabsorption.
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