Question

What is it called when a drug is no longer effective but organism is susceptible in vitro?

Answer 1

When a drug is no longer effective but an organism is susceptible in vitro, it is called intermediate.

What is it known as when a drug loses its effectiveness but an organism is still susceptible in vitro?

• When a bacterial strain is susceptible in vitro to a concentration of an antibiotic drug that is linked to a questionable therapeutic effect, it is said that the bacterium's sensitivity to that antibiotic is intermediate. Thus, When a drug is no longer effective but an organism is susceptible in vitro, it is called intermediate.
• The designation "intermediate" suggests that while the same antibiotic may not be sufficiently effective against the same organism if it is located in other places, such as the meninges, it may readily be eliminated in bodily compartments that are easily accessible by the medicine, such as the urinary tract.

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