The most significant limitation to the clinical utility of anthracycline antineoplastic medicines, which include doxorubicin (adriamycin), daunorubicin, or epirubicin, is the danger of cardiotoxicity.
Nevertheless, these substances continue to rank among the most popular anticancer medications.
Although the oxidative stress-based concept involving intramyocardial formation of reactive oxygen species (ROS) has acquired the most respect, the molecular etiology of anthracycline cardiotoxicity is still quite debatable.
Through redox cycling of both their aglycones and anthracycline-iron complexes, anthracyclinesmay facilitate the generation of ROS.
Given the remarkable cardioprotective efficacy of dexrazoxane, this suggested mechanism has gained a lot of traction (ICRF-187).
What is Influenza?
It affects the lungs, nose, and throat.
High-risk groups include young children, elderly individuals, pregnant women, persons with chronic illnesses, and those with weakened immune systems.
Fever, chills, muscle pains, cough, congestion, runny nose, headaches, and exhaustion are some of the symptoms.
Rest and fluids are the main treatments for the flu because they allow the body to fight the illness on its own.
Anti-inflammatory painkillers sold over-the-counter may aid with symptoms. An yearly flu shot can lessen complications and aid in prevention.
