Question

multigene families include two or more nearly identical genes or genes sharing nearly identical sequences. a classical example is the set of genes for globin molecules, including genes on human chromosomes 11 and 16. how might identical and obviously duplicated gene sequences have gotten from one chromosome to another?

Answer 1

Identical and obviously duplicated gene sequences have gotten from one chromosome to another by chromosomal translocation.

In terms of genetics, a translocation takes place when chromosome fragments and the (often two) fragmented portions reassociate with other chromosomes. For the diagnosis of several genetic diseases and syndromes, the finding of chromosomal translocations can be crucial.

Multigene families are groups of related or identical genes that have developed by gene duplication. It is thought that a single ancestral gene was duplicated and varied to create multigene families. The multigene families that code for actins, hemoglobins, immunoglobulins, tubulins, interferons, histones, etc. are a few examples.

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