humans with the sickle cell mutation suffer from sickle-cell disease which is often fatal. despite that fact, certain areas of a

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1 year ago

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humans with the sickle cell mutation suffer from sickle-cell disease which is often fatal. despite that fact, certain areas of a

frica which have a high incidence of malaria are inhabited by human populations, in which the sickle-cell mutation has a very high prevalence. how can we explain that?

Biology

1 answer:

Stells [14] · Answer 1 · 2024-03-21T15:02:59+03:00

In certain areas of Africa, the sickle cell mutation has a high frequency because it confers an adaptive advantage against malaria which is endemic to this region.

<h3>What is natural selection?</h3>

Natural selection is a mechanism that drives evolution in natural populations, which in case we are observing stabilizing selection because it acts to stabilize the frequency of different alleles.

In certain regions in the African continent, the sickle cell mutation exhibits a high frequency since it is able to confer resistance against malaria which is an endemic disease located in this region.

Therefore, with this data, we can see that stabilizing selection acts to increase the frequency of the sickle cell mutation, which is harmful in regions where malaria is not endemic but increased in certain parts of Africa due to the incidence of malaria, thereby being an adaptive trait for these geographic areas.

Learn more about stabilizing selection here:

brainly.com/question/8563440

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