The type of earth surface is
Cool ocean
Numerous degenerative neurological conditions, most notably Parkinson's disease, have been linked to an excessive buildup of alpha synuclein (a-syn) in the brain. Intraneuronal inclusions, often known as Lewy bodies, are neuropathological characteristics seen in Parkinson's disease, Lewy body dementia, and other synucleopathies. The aggregation of a-syn is their main structural component. A-syn accumulation, aggregation, and ensuing Lewy body formation can be attributed to a variety of biological processes. These include genetic changes in parkin, synuclein, or the deubiquitinating enzyme ubiquitin C-terminal hydrolase (UCH-L1), which results in less efficient removal of a-syn via the ubiquitin proteasomal pathway (UPP). Additionally, environmental variables and an age-related decline in antioxidant defense mechanisms that heighten oxidative stress and can have an impact on the formation or clearance of a-syn are intracellular insults.
We focused on changes in the aggregation and clearance of a-syn as impacted by the UPP and the oxidative stress pathways in our dynamic models of a-syn processing in both normal and various disease states. A free radical profile similar to that observed in vivo after exposure to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is produced during simulation of enhanced oxidative stress (MPTP). To replicate the kinetics of a-syn that correlates to the neuropathology reported for the sporadic and hereditary types of Parkinson's disease, different model parameters of oxidative stress, UPP failure, or both routes are used. With the use of this in silico model, it is possible to evaluate the kinetics of pathway elements and more accurately identify and validate key pharmaceutical targets.
Learn more about Parkinson's disease brainly.com/question/28169444
#SPJ4
Athletes need a lot of protein and it is unhealthy for a athlete to become vegetarian Bc they don’t have anything to burn off during the sport
Answer:
Co-dominance because he expresses both of the alleles simultaneously
Explanation:
The ABO blood group system is used by humans. This blood group type is controlled by multiple alleles. Alleles A and B are both dominant over allele O but are co-dominant. Co-dominance is a type of inheritance pattern in which two alleles of a gene both express themselves i.e. neither is recessive.
This is the case of this family whose parents have a genotype of AO (blood type A) and BO (blood type B) respectively. The children have blood types A, B, and AB. However, the child with genotype AB possesses both the A and B allele, which are both expressed in his blood group (phenotype), hence, it can be said that the child is exhibiting CO-DOMINANCE for the blood group trait.
Answer:
In the chloroplast.
Explanation:
Chlorophyll is a green pigment plants use to absorb light so they can make food via photosynthesis. Chloroplasts are organelles that contain chlorophyll, so it only makes sense that the best answer is the chloroplast.
