Answer:
A. 14.59
Explanation:
Firstly, rounding a number means making a number simpler but keeping its value close. So rounding 14.587020 means making it look less complex but making sure the rounded value is within range of the original value.
Next, we have to know that to round a number;
* Digits below 5 (<5) rounds down the next digit to their left i.e. we leave the digits the same and turn the rounding digit to 0.
* Digits above 5 (>5) rounds up the next digit to the left i.e. we add 1 to the next digit
Next, to round to 4 significant digits means we want to see only the first four non-zero digits in our value. Note that, all non-zero digits i.e. 1-9 are significant
Hence, 14.587020 will be:
= 14.587020
= 14.58700
= 14.59000
We have four (4) digits which are non-zero already, hence we stop here and remove all zeros to the right
Hence, 14.587020 to 4 significant digits is 14.59 i.e. 14.587020 ~ 14.59
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Answer: Missense mutation
Explanation:
Missense mutation is a type of point mutation where a single nucleotide is changed to cause substitution of a different amino acid. This in turns render the resulting protein non-functional.
In the case of sickle-cell disease, the sixth amino acid in the gene sequence, glutamate (GAG) is substituted with valine (GUA), due to Adenine nucleotide changed to Uracil nucleotide. Thus, missense mutation has occurred
