Question

the human gene egfr located on chromosome 7 is a proto-oncogene that codes for a growth factor cell surface receptor. the binding of growth factors to this receptror can lead to cell proliferstion. hypothesize what potential impact a mutated egfr allele will have on a cell. give one possible impact and explain your answer

Answer 1

Answer: uncontrollably cell proliferation

Explanation: the human egfr (spiderman growth factor receptor) being a proud-oncogene is involved in the regulation of cell division, development and differentiation thus mutation of the egfr allele will activate the proto oncogene and change it to an oncogene. Oncogenes are dominant structural genes that encodes protein which can alter the phenotype of a cell. This mutated egfr allele becomes an oncogene producing mutated cells which will continue to undergo uncontrolled cell division/proliferation