You asked which theory is most widely accepted describing the formation of our universe? …. Big Bang Theory
In eukaryotic cells the DNA can be found in the nucleus mainly. so DNA replication takes place in the nucleus during the S phase of the cell cycle.
Also in eukaryotic cells there are mitochondria and chloroplasts (plants) and these have circular DNA and they also get replicated (according to their own mechanism).
Prokaryotic cells don't contain a nucleus. They do not contain DNA in the cytoplasm and thus the DNA replication will take place here.
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The correct response in this case would be denature, the enzyme will no longer be able to catalyze the reaction if there is an abnormally high change in the pH or the temperature.
Answer:
It means that it is trying to increase it's infectivity rate and its survivability rate in different environments.