Answer:
When you sit on a plane for 6 hours without moving, blood accumulates in your veins, and the moment you get up, gravitational forces affect venous return, cardiac output, blood pressure, and venous pressure. That way, when you're sitting on a plane, the gravitational force is the same at the upper and lower extremities, such as the chest, abdomen, and legs, causing venous blood pressure and volume to be evenly distributed throughout the body. However, when one gets up, one becomes dizzy because of abnormal regulation of blood pressure. This is because gravity causes blood to accumulate in the lower extremities (veins of the legs and trunk). This lowers the blood pressure and the blood that the heart pumps. By causing blood to accumulate in the lower extremities, and as venous compliance increases, the veins expand with blood that causes the volume of blood to shift in the veins. This increases the volume and venous pressure in the lower extremities when standing. And the volume of thoracic venous blood is less and less central venous pressure. This leads to a decline in stroke volume. Cardiac output and mean arterial pressure also decrease as left ventricular stroke volume decreases, reducing pulmonary venous return. Decreased standing blood pressure, referred to as orthostatic or postural hypotension. Thus, lowering blood pressure decreases cerebral blood flow, which means less range of blood in the brain causing dizziness.
Explanation:
The question is incomplete. The complete question is:
Question: Why do organisms without oxygen need to convert pyruvate to lactate?
A) because pyruvate is toxic to the cells
B) in order to regenerate NAD+
C) in order to use lactate in the citric acid cycle
D) because lactate is needed to produce ATP
Answer:
B) in order to regenerate NAD+
Explanation:
Kreb's cycle and electron transport chain (ETC) are the aerobic stages of cellular respiration. ETC regenerates NAD+ and FAD+ by oxidation of NADH and FADH2 produced during glycolysis and Kreb's cycle. Here, oxygen serves as the terminal electron acceptor.
Glycolytic reactions use NAD+ as an electron acceptor and produce NADH. Therefore, a constant supply of NAD+ is required to sustain glycolysis. In absence of oxygen, ETC cannot occur and organisms convert pyruvate into lactate. Pyruvate is reduced in lactate and NADH serves as the electron donor. Thereby, lactate fermentation regenerates NAD+ to continue the process of glycolysis.
The cells would cease to function <span>after a relatively short amount of time (a few years at best, depending on the amount of cells that part normally has). A living being's body parts would also never grow. They would stay the same size since they were born. The only good result is that without mitosis, cancer wouldn't occur.</span>
Solid inner core, hope this helps, 4300*C.
A system that allows pharmacists to automatically substitute with certain pharmacologic or therapeutic alternatives without calling the prescriber each time is known as a Therapeutic interchange.
Therapeutic interchange is the practice of replacing, with the prescribing practitioner's approval, a prescription medication originally prescribed for a patient with an alternative prescription medication. Therapeutic drug monitoring (TDM) is testing that measures the amount of certain medicines in your blood. It is done to make sure the amount of medicine you are taking is both safe and effective.
Therapeutic drug monitoring helps in designing patient-specific dosage regimen, it aids in enhancing the efficacy of drugs, to reduce the toxicity of drugs and for diagnostic purposes, by individualizing drug therapy.
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