B. Gases because it increase by less
Numerous degenerative neurological conditions, most notably Parkinson's disease, have been linked to an excessive buildup of alpha synuclein (a-syn) in the brain. Intraneuronal inclusions, often known as Lewy bodies, are neuropathological characteristics seen in Parkinson's disease, Lewy body dementia, and other synucleopathies. The aggregation of a-syn is their main structural component. A-syn accumulation, aggregation, and ensuing Lewy body formation can be attributed to a variety of biological processes. These include genetic changes in parkin, synuclein, or the deubiquitinating enzyme ubiquitin C-terminal hydrolase (UCH-L1), which results in less efficient removal of a-syn via the ubiquitin proteasomal pathway (UPP). Additionally, environmental variables and an age-related decline in antioxidant defense mechanisms that heighten oxidative stress and can have an impact on the formation or clearance of a-syn are intracellular insults.
We focused on changes in the aggregation and clearance of a-syn as impacted by the UPP and the oxidative stress pathways in our dynamic models of a-syn processing in both normal and various disease states. A free radical profile similar to that observed in vivo after exposure to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is produced during simulation of enhanced oxidative stress (MPTP). To replicate the kinetics of a-syn that correlates to the neuropathology reported for the sporadic and hereditary types of Parkinson's disease, different model parameters of oxidative stress, UPP failure, or both routes are used. With the use of this in silico model, it is possible to evaluate the kinetics of pathway elements and more accurately identify and validate key pharmaceutical targets.
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your body and nature is about human life
Answer:
If the transgenic salmon escapes from their pens into the ocean population there are chances that they would compete with the wild salmons for food and space. They may also bring new diseases and changes to the food webs and ecosystem of the ocean.
Explanation:
A transgenic organism or genetically modified organism is the one that undergoes alternation through recombinant DNA technology.
No, I do not think that FDA should approve Aquabounty of growing and selling transgenic salmon since there is higher chance that they may interfere and disturb with the ecosystem and might also bring new diseases.
BioSafety Level (BSL) 3 labs,
perform work with indigenous or exotic agents that may cause serious or
potentially lethal diseases through the inhalation exposure. Biological Safety
Levels (BSL) are a sets of protections assigned to the activities that occur in
specific biological laboratories. BSL protects laboratory workers, the
surrounding environment and also the community.
