Although at first it may seem like an antigen, it's a pathogen.
Answer:
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Secondary immunodeficiency is a deficiency or defect in body's immune system.
10 common diseases that can cause a secondary immunodeficiency are:
leukemia
diabetes
skin cell diseases
burns
virus infection
lymphoid malignancy
nephrotic syndrome
neutropenia
human immunodeficiency virus
protein-calorie malnutrition
There is no known way to prevent inherited immunodeficiency disorders. but there is some ways to prevent infection like get enough sleep, keep clean, manage stress, eat right etc.