Answer:
The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.
In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.
Explanation:
Answer:
0.27m
Explanation:
To get the energy
Potential energy= Mgh
M is Mass
G is acceleration due to gravity
H is height..
M= 0.29kg, h= ?
P=0.759. g=9.8m/s
Therefore,
0.759=0.29×9.8×h
H= 0.759÷2.842
H= 0.27m
The answer is <span>The name includes the genus and species.
In binomial nomenclature, the name of the species consists of two (Greek: bi-) names or terms (Greek: nome). According to this system, t</span>he first word indicates the genus classification of an organism and the second word indicates the species within a genus. For example, Latin name for a white oak is Quercus alba and for a red oak is <span>Quercus rubra</span>. Quercus is the name of the genus and it includes both white oak (Q. alba) and red oak (Q. rubra). The second words - alba and rubra, respectively, indicate the name of the species within the genus Quercus.<span>
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