Aggregate...tell me how you do on the test!:)
Substance abuse refers to the harmful or hazardous use of psychoactive substances, including alcohol and illicit drugs.
The answer would be A.
The question you have to ask is, is it possessive?
Yes it is possessive.
The wing is owned by the bird. Its wing was broken.
It's means it is or it has.
It's would not make sense in this case because you can not put it is or it has into this sentence.
The correct answer is She had a lovely house, many friends, and an impressive body of work.