Question

Describe how a faulty protein alters the movement of chloride ions across the cell membrane. How does this change in the cell membrane lead to the symptoms of cystic fibrosis? Type your answer here.

Answer 1

Problem of protein alters the movement of Ions

Explanation:

• Proteins are tiny machines that do explicit occupations inside a cell. The directions for building every protein are encoded in DNA. Proteins are gathered from building squares called amino acids.  
• The CFTR protein is comprised of 1,480 amino acids. When the CFTR protein chain is made, it is collapsed into a particular 3-D shape. The CFTR protein is formed like a cylinder that experiences the film encompassing the cell, similar to a straw experience the plastic top on a cup.
• In individuals with CF, changes in the CFTR quality can cause the accompanying issues with the CFTR protein:  
• It doesn't function admirably  
• It isn't delivered in adequate amounts  
• It isn't delivered in any way  
• At the point when any of these issues happen, the chloride particles are caught inside the cell, and water is never again pulled in to the space outside the cell. When there is less water outside the cells, the bodily fluid in the aviation routes gets got dried out and thickens, making it smooth the cilia. The cilia can't clear appropriately when thick, clingy bodily fluid overloads them.