Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
Answer:
1. Both neutron stars and black holes are the corpses of stars that died in explosions known as supernovas. Black holes form when the most massive stars die and neutron stars form when stars not as large die. They both have a very strong gravitational pull, but a black hole's pull is stronger than a neutron star. Neutron stars <u>will turn into</u> black holes if the force of gravity breaks the resistance of electrons.
2. White dwarfs are degenerate, which means they can compress matter. The material in a white dwarf no longer undergoes fusion reactions, so it is supported only by electron degeneracy pressure. This causes it to be extremely dense, saving space and energy.
3. A light year is the distance light travels in a year while an astronomical unit is the average distance between the earth and the sun.
4. A convection zone transfers energy by radiation and conduction.
Assuming a 10% trophic efficiency, the herbivore (primary consumer) will get 10% of the producer energy. Then, the second consumer that eat the herbivore will get 10% of the primary consumer energy, so it is 10%*10%= 1% of the primary producers.
Then, the t<span>ertiary consumer should get 0.1% of the primary producers' energy.</span>
Im like 98% sure its B because ultra sounds hear the frequency's of the baby in the womb
