Answer:
Bridgham et al. (2006) showed that the interaction between a steroid hormone (aldosterone-M) and its receptor (mineralocorticoid) evolved by Darwinian gradualism. In this work, the authors demonstrated a primitive affinity between the hormone and its receptor that was initially present in chemically similar but more ancient ligands. This result has implications in understanding the association between gene duplication and the evolution of hormone signaling pathways. For example, in invertebrates, this work reinforces the importance of gene duplication in the existing interaction between paralogous glucocorticoid receptors and their receptor mineralocorticoid genes that were derived from duplication (Thornton 2001).
The publications above cited are the following:
J.T. Bridgham, S.M. Carroll, and J.W. Thornton (2006). Evolution of hormone-receptor complexity by molecular exploitation. Science, 312(5770), 97-101.
JW Thornton. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions, Proc Natl Acad Sci USA (PNAS), 2001, vol. 98 10 (pg. 5671-5676).
I think the correct answer from the choices listed above is the first option. THe tool that would be <span>useful for testing cleavage and fracture in a mineral would be a hammer. It can test how a mineral acts when subjected to a very large amount of pressure or force. Hope this answers the question.</span>
C, energy
to regenerate ATP is the chemical energy stored in food like glucose
