I believe the answer is B
Answer:
a) The substrate 2 will be accumulated in the cells.
b) The enzyme E is mutated
Explanation:
a) The enzyme C has a mutation, the substrate 2 will not be turn into substrate 3 and this will cause to accumulation of 2.
b) when cells have 1,2,3 or 4 because of mutation of E non of these substrates cannot lead to 5. but ıf 5 gıven from the diet, the individuals can survive.
Explanation: As the DNA is present in the nucleus, there is compartmentalisation and the process becomes more efficient without the interaction of external bodies. The membrane of the nucleus protects the DNA from injuries.
<u><em>Pls mark Brainliest</em></u>