I'm certain the answer is liquid. I hope this helps you! <3
We administered 300 mg of clindamycin intravenously at 12-h intervals for 2 days to patients with acute and chronic hepatitis, cirrhosis, and controls to determine whether clindamycin will exacerbate preexisting hepatic dysfunction or whether drug excretion will be delayed in patients with liver disease
Answer:
The positive charge of the histone proteins get reduced due to the process of histone acetylation, thus making the wrapping of DNA around the histones less tightened. The loose connected DNA afterward associates with the transcription factors for the articulation of the genes situated in that area.
Generally, when there is no requirement of gene anymore, the acetyl groups from the histones get withdrawn by the activity of histone deacetylase enzyme (HDAC9) that makes the DNA tightly wrapped and inaccessible again. In case, when less expression of histone deacetylase enzyme occurs, the process of deacetylation fails to take place. This indicates that within an immune cell, at the time of infection, the inflammatory gene, which was made available does not get re-wrapped firmly around the histones.
It is true that studies of animals show that they play only when the physical survival needs have been met; however, there is growing evidence that for children, play is crucial in terms of biological evolution as well as individual development.
