Which of the following types of mutation, resulting in an error in the mRNA just after the AUG start of translation, is likely t
o have the most serious effect on the polypeptide product? A) a deletion of a codon
B) a deletion of two nucleotides
C) a substitution of the third nucleotide in an ACC codon
D) a substitution of the first nucleotide of a GGG codon
E) an insertion of a codon
The correct answer is option B) "a deletion of two nucleotides".
Explanation:
A frameshift mutation is a type of genetic modification caused by the insertion or deletion of one or more nucleotides in a position that results in changing the sequence at which codons are translated in the ribosome. Frameshift mutations have the most serious effect on the polypeptide products since it results in changing completely the sequence of the protein. A deletion of two nucleotides after the AUG start of translation would result in a frameshift mutation, therefore this mutation would have the most serious effect on the polypeptide product.
Since 100% of your DNA decides how you look, if even one thing changes, one part of your look would change. Sometimes it's something big like eye color, or sometimes like a small change in skin color.
That scrape on our knee will never heal and the blood loss due to bleeding will never be replaced. This is because RNA is inside of cells and without the ability to create new RNA you cannot replace missing cells. So the scrape will never heal if your cells cannot create new RNA.
