If you were to go into his brain, you may see <u>abnormal tau expression.</u>
<h3><u>What does tau exhibit itself abnormally?</u></h3>
Dysfunction results from tau's aberrant expression. Dysfunction in the mitochondria and peroxisomes is caused by tau overexpression. Oxidative stress is simultaneously exacerbated by mitochondrial dysfunction, and peroxisome dysfunction and oxidative stress itself have the capacity to exacerbate all three dysfunctions.
When tau is cleaved by proteases downstream, shortened tau is produced, which aggravates mitochondrial dysfunction even further. Tau phosphatase (PP2A) activity is decreased by oxidative stress while tau kinase (GSK-3, JNK) activity is increased.
This leads to an increase in tau phosphorylation and a reduction in tau's capacity to connect to microtubules. Tau aggregates as a result of hyperphosphorylation, which is accelerated by oxidative stress.
Learn more about abnormal tau expression with the help of the given link:
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Answer:
The best answer to the question: In other words, which principle states that electrons will occupy equal-energy orbitals so that a maximum number of unpaired electrons results? Would be: Hund´s Rule.
Explanation:
We must first remember that electrons are negatively charged, and therefore, they will tend to reject each other when they get close together. As such, electrons tend to seek such separation by initially filling up orbitals that have not yet been occupied by other electrons, starting from those at the sublevels and moving to the higher energy levels, and later they might start pairing up. The one rule that states this exactly, and explains the way that electrons will first fill up orbitals singly, and then later on start the pairing process, is known as Hund´s rule.
Answer:
The correct response is Option B. A set of processes.
Explanation:
Political anthropologists see each state in each country as historically and culturally unique. It is an amalgamation of different practices and behaviors that have solidified over time gradually so that laws and institutions incorporate cultural assumptions and things we take for granted. Like the notion of freedom in the United States being an important part of civil rights. This value or moral is an integral part of American culture and how we make sense of government practices and our role in American society.
Answer:
This would be a simple situation of a brother following his older sibling.
Explanation:
I've seen this before.
Even though Isaiah has been taught by his teachers and/or parents not to use drugs, he will try it if he sees his brother trying it without the consequences he has heard of from his teachers and/or parents.
Unless the older sibling has done anything wrong in the younger sibling's eyes, the younger sibling will always look up to his older brother/sister. Even if the younger brother has been taught over and over again not to do something because of the horrid consequences that come with it, he will do it if he sees his brother doing the same without the consequences specified.
In other words : If the older brother hasn't been caught by anyone for using drugs, the younger brother will follow suit, or at least try to do the same.
Hope this helps.
Fungi,animalia,protista,plantae,eubacteria,archaebacteria
