Question

Use the mutation lab to answer the question below. In the lower half of the lab, change the template DNA strand such that the sequence ACAAAC. is changed to ..ACATAC.. Which of the following terms correctly describes this type of mutation?
a.substitution
b. inversion
c. deletion
d. insertion

If this mutation occurred in a protein-coding gene, how would it be classified?

a. silent mutation
b. nonsense mutation
c. frameshift mutation
d. missense mutation

Answer 1

Answer:

Substitution, missense mutation

Explanation:

Mutation is a change in the DNA sequence that can subsequently alter the genetic message.

Substitution mutations occurs when a base is replaced with another different base.

A good example is the one given in the question where the third A in the sequence ACAAAC is replaced by a T.

If this kind of mutation occurs in a protein-coding gene, it will be classified as a frameshift mutation.

Missense mutation is caused when there is a change in a single nucleotide that results to the coding of a different Amino acid

Answer 2

Answer:

Substitution mutation and missense mutation respectively.

Explanation:

Mutation is any heritable change of the base-pair sequence of genetic material.

Substitution mutation often affects only a single codon.

The question shows that ACAAAC. is changed to ..ACATAC ... We see that the 4th nucleotide A is changed to T. This shows the substitution that happened.

Their effect of substitution may not be serious except they affect an amino acid essential for the structure and function of the finished protein molecules an example is the sickle cell anaemia resulting from a missense mutation.