I. Heat is not readily available to all living cells.
II. Heat at excessive amounts denatures proteins.
III. Heat does not provide the activation energy for their reactions.
IV. When a critical temperature is reached, proteins no longer function
Answer;
I and IV
Explanation;
Living cells cannot use heat to provide the activation energy for biochemical reactions because heat is not readily available to all living cells and also when a critical temperature is reached, proteins no longer function.
Too much heat can kill an organism by rendering its organelles, cells, tissues and organs permanently inoperable and un-salvageable. The same process can be observed in tissues at low temperatures, and is the cause of frostbite. This is because enzymes are denatured by high temperature and inactivated by low.
That's what is called competitive enzymatic regulation. If there are more of that substance than the enzyme substrate, then most of the enzyme, if not all depending on the substance's concentration, will be inhibited on its action. If there are more substrate then the competitive substance, the expected reaction for that enzyme will happen at an expected rate. If the ratio substrate:substance is 1:1 then the reaction enzyme-substrate is very slowed down.
The nurse should explain that myelosuppression is a common side effect of cancer treatments. The healthcare provider should explain to the patient that it is better to reduce or stall the treatment for a while because it would be more harmful to them if they continued.
