Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
Answer:I believe B:The Phosphate Group
Explanation:
Petroleum Products
Petroleum and its products are mainly composed of carbon polymers (chains), as the backbone, with different structural and functional groups. Plastic, for example, is made of polypropylene and polybutylene which is mainly made of carbon atoms, whose monomers are linked in a chain to form polymers that make up the products.
Synthetic rubber on the other hand is made of copolymers of carbon and other addictives such as styrene. Synthetic fiber is made of nylon that is composed of a copolymer between carboxylic acid and amides.
Answer:
b. methylation.
Explanation:
Science can be defined as a branch of intellectual and practical study which systematically observe a body of fact in relation to the structure and behavior of non-living and living organisms (animals, plants and humans) in the natural world through experiments.
Genome editing can be defined as a high-tech process which avail scientists the opportunity or ability to remove (delete), replace and insert Deoxyribonucleic Acid (DNA) sequence in a living organism such as bacterias, animals, plants etc in order to correct a genetic disorder and to improve on their physical and chemical conditions.
Transcription can be defined as a process which typically involves re-writing the informations contained within a Deoxyribonucleic Acid (DNA) into a Ribonucleic Acid (RNA) by enzyme RNA polymerase.
Hence, DNA regions that are transcriptionally silenced by hypercondensation have often undergone a modification of their cytosine residues termed methylation.
For example, CpG island methylation transcriptionally silences about 650 to 800 genes in patients suffering from colorectal cancer.
Explanation:
the name porifera means pore bearer in latin. a sponges body is covered by a skin, one cell thick. this skin has lots of small pores ad a few large openings. the small openings are the entrances to a complex system of channels. these collar cells pump water through the entire sponge and filter out food for the sponge cell to eat
