MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
The cell cycle ensures the duplication of the genome and its distribution in daughter cells by passing through a coordinated and regulated sequence of events.
A series of checkpoints guarantee the orderly progression of the phases of cell division and the correct distribution of the duplicated genetic material in the daughter cells.
The checkpoints during mitosis are:
- At the end of stage G1 and before S.
- Before anaphase in mitosis.
- DNA damage checkpoints in G1, S or G2.
The checkpoint before anaphase in mitosis guarantees the separation of chromosomes, and operates by activating the Mad2 protein that prevents the degradation of segurin, until the conditions are appropriate.
That is, the Mad2 protein prevents the segregation of sister chromatids until they have all bound to the spindle.
Therefore, we can conclude that MAD (mitotic arrest deficient) are proteins related to spindle cell cycle checkpoint and it is important since they prevent the segregation of sister chromatids until all have bound to the spindle.
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Answer:
A mutation that cause changes to short stretches of nucleotides. These mutations affect the specific genes that provide instructions for various functional molecules, including protein . changes in these molecules can have impact on any number of an organism's physical characteristics
Answer:
first one is a point mutation
second is a frame shift by addition
Explanation:
First one : only one letter changes
second one : a letter was added shifting other bases.
Okay. The destruction of tundra vegetation will not really freeze the soil or deepen the active zone much. Therefore, A and C are eliminated. The destruction of the vegetation can actually melt permafrost, which contributes to global warming. The answer is D.
Explanation:
Two important ways by which humans have affected the carbon cycle, especially in recent history, are: 1) the release of carbon dioxide into the atmosphere during the burning of fossil fuels, and 2) the clearing of trees and other plants (deforestation) that absorb carbon dioxide from the atmosphere
