The hypothesis by Coleman was that the product of the ob+ gene was the appetite suppressing hormone. Hence, the homozygous ob/ob mutant are in a position to synthesize that hormone, and its circulating level would be zero. He also hypothesized that the product of the db+ gene was the receptor for the appetite-suppressing hormone. Thus, the homozygous db/db mutant would be able to synthesize the hormone but would not be in a position to respond to it. It would eat excessively and produce large amounts of body fat, which in turn would produce large amounts of appetite-suppressing hormone . In the absence of a receptor, the db/db mutant's hormone level would remain abnormally high.
Coleman's hypothesis were confirmed when the precise functions of the ob+ and db+ genes were determined. The peptide hormone encoded by the ob+ gene was named Leptin.
The velocity of the object is similar to speed but has one main difference: velocity takes into account the direction of an object. Since speed does not take direction into consideration, it is considered to be a scalar quantity. Thus, the speed of an object can never be negative.
Warmer, colder
Convection is the transfer of heat by the movement of a fluid (liquid or gas) between areas of different temperature.
Warmer fluid is less dense so it rises and colder fluid is more dense so it sinks.
Part of the brain,superior and anterior to the brain stem. Inferior to the thalamus a section of the brain responsible for hormone production. Also responsible for the direct control of the endocrine system through the pituitary gland.
Answer:
B
Mutation is the ultimate source of genetic variation, but mechanisms such as sexual reproduction and genetic drift contribute to it as well Because prokaryotes are haploid, such a mutation immediately become part of the genetic makeup of the cell unlike eukaryotic diploids where a normal second copy of the gene usually protects the cell from the potentially lethal effect of such a mutation.
