Answer:
Genetic engineering may be defined as the process that involves the manipulation of genetic material of the organisms to develop the organisms with required characteristics. Natural selection is the process of selection of traits that allow the organisms to adapted in their environment.
Natural selection and genetic information both involve the transfer of genetic information form one generation to to next generation as manipulated genetic material of parent organism.
Beneficial trait is selected in both natural selection and genetic engineering.
Genetic engineering involves desired modification of traits and is faster than natural selection. Natural selection works over generations.
Genetic engineering and natural selection is applicable on all organisms, including humans.
Natural selection only select the individual that have beneficial traits for survival an other individual gets extinct from the population. Therefore, natural selection does not work on entire population.
Thus, the options 1), 3), and 4) are correct.