Chromosomes attach to spindle fibres by their centromeres during metaphase of mitosis.
Further Explanation:
Interphase is the resting phase or metabolic phase of a cell where it prepares itself for the cell division process. Interphase comprises of sub-phases namely, Gap1 phase, Synthesis phase and Gap2 phase. G1 is the first gap phase where a cell grows larger in size and the cytoplasm volume increases as more organelles are produced. During Synthesis phase, the strands of DNA replicates. G2 is another gap phase in which the cell becomes much larger in size and this phase is followed by mitosis where cell division occurs.
Mitosis or somatic cell division is comprised of four phases which includes prophase, metaphase, anaphase and telophase. A somatic cell divides to give rise to two identical daughter cells where each cell contains exact copy of each chromosomes present in the parent cell. In the prophase, the envelope that covers the nucleus and nucleolus disappears and chromosomes become visible by forming two chromatids attached to centromere.
In the metaphase, chromosomes alignment at the metaphase plate occurs and spindle fibres attach to the centromere. Spindle fibres pull the chromatids away from the metaphase plate towards the opposite poles of the cell during anaphase. In the telophase, nuclear membrane reforms, chromosomes decondense and nuclear membrane reforms around each daughter nuclei. The cytokinesis is the final stage of cell division process where the parent cell is pinched off to result in two daughter cells.
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Answer Details:
Grade: High school
Subject: Biology
Chapter: Cell division
Keywords: Mitosis, prophase, metaphase, anaphase, telophase, interphase, cytokinesis, somatic cell, nucleolus, nucleus, centromere, chromatids, spindle fibres.
