The center of the world is the equator
Gradual changes in the frequency of diseases over long periods are known as SECULAR TIME TRENDS. For example, the rate of mortality in USA due to coronary heart diseases over a period of time. Onset of puberty in girls is also a secular time trend.
Secular time trend is also referred as Secular Variation and Secular Drift.
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Carbon dioxide (CO2) and water (H2O)