ORF alignments above a certain threshold level with one or more genes in the database are presumed to encode a protein of similar function and such pairs are called Orthologues. They diverged by speciation.
<h3>What are orthologue genes?</h3>
Orthologue genes are genes that evolved by divergence from a common ancestor.
In general, orthologue genes have the same function in different species, but they exhibit sequence variation.
The alignment between orthologue genes exhibits sequence homo-logy in evolutionarily conserved gene regions.
Learn more about orthologue genes here:
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Sepsis will cause increased permeability of the capillary, causing edema which was the water to go in the interstitial layer. Make the thin wall become fatter. This will cause the distance between capillary and the alveolus become further, thus making the gas diffusion is harder and less oxygen gained. That is why sepsis patient might get some difficulty in breathing.