Washington choosing diverse thinkers for his cabinet shows his ability to recognize his weakness in understanding politics and recognizing the talent and intellect of others to guide his presidency.
Hamilton at Secretary of Treasury was more effective because he had more influence over the actions Washington took. Washington supported the National Bank and creation of federal currency as suggested by Hamilton. He also shared Hamilton's view of neutrality toward the French and English during their war.
Though Jefferson proved to have an impact. His desires as Secretary of State were not met by Washington. Jefferson wanted to create an alliance with France and assist them in their war against England. In addition he did not support Washington's action against the Whiskey Boys. Ultimately, Jefferson's lack of influence led to him creating an opposing political party to the Federalists.