What is a wave and what does it do

Linda owns an orchard of orange trees, and she is worried because she notices that many of her orange trees are unhealthy. They

ANTONII [103]

Answer:

If there is low genetic diversity, she needs to introduce something into the system to increase the variation. I would suggest breeding the orange trees with other new orange trees to change the allele frequencies, which is called gene flow.

Likely the fungi are attacking them somewhere that they have decreased resistance, and if more alleles were introduced, there would probably be evolution towards a genotype that promotes defense against these fungi.

7 0

2 years ago

What is the application of Gene Editing in Primary T Cells?

Lelu [443]

Answer:

Creative Biogene CRISPR/Cas9 Platform provides comprehensive gene editing services for various cell lines, especially for primary T cells. With years of experience, our talented scientists have established an efficient assay to edit genome in T cells by CRISPR/Cas9. At CRISPR/Cas9 PlatformCB, we offer a gene knockout service for customer as well as isolation of primary T cell service. Based on our excellent platform, our staff are focusing on supplying the best services and products.

5 0

2 years ago

QUESTION 1 (5 marks) A molecule of messenger RNA (mRNA) has just been synthesized and processed in the nucleus of human cell wit

Dmitry [639]

1) DNA Template strand: TACAATCGACCCATC. 2) Anticodon: AAU. 3) mRNA carries genetic information to build the protein. 4) 5 amino acids. 5) Amino acids: Met, Leu, Ala, Gly, Tyr.

1)

<h3>What is the template strand?</h3>

When the DNI molecule separates into two strands to form the transcription bubble, we can identify two separate segments:

The coding strand that goes in 5' to 3' direction
The complementary strand -template strand- that grows in 3' to 5' direction .

The template strand is the one that is going to be complemented by the mRNA.

mRNA ⇒ AUGUUAGCUGGGUAG

DNA ⇒ TACAATCGACCCATC

Remember that pairs are as follows

T → A

A → U

G → C

2)

<h3>What is an anticodon?</h3>

The anticodon is the sequence of three nucleotides that couples with the mRNA codon.

Each tRNA has two important sites. One of them is the anticodon that couples with the codon of the mRNA molecule. The other one carries the amino acid that is going to be addeded to the protein.

1st 2nd 3th 4th 5th

mRNA codons ⇒ AUG UUA GCU GGG UAG

tRNA anticodon ⇒ AAU

3)

<h3>What is translation?</h3>

Translation is the stage of protein synthesis during which mRNA carries genetic information needed to synthesize the new protein in the cytoplasm.

Steps,

1- The formed mRNA moves to the cytoplasm through the nucleus membrane pores.

2- Once in the cytoplasm, mRNA meets a ribosome, the primary structure for protein synthesis.

3- Ribosomes are organelles composed of the association of proteins with rRNA and tRNA. They can be found in the rough endoplasmic reticulum or floating in the cytosol.

4- While the ribosome reads mRNA strain from its 5' extreme to 3', tRNA adds the correct amino acids to build the polypeptide.

The function of mRNA during translation is to take genetic information needed to build the protein.

4)

<h3>How many amino acids are determined per codon?</h3>

Each codon codes for only one amino acid.

There are cases in which different codons code for the same amino acid, but a single codon always codes for one amino acid.

mRNA codons ⇒ AUG UUA GCU GGG UAG

Amino acids ⇒ Met Leu Ala Gly Tyr

1 2 3 4 5

This mRNA segment represents 5 amino acids.

5)

Amino acids ⇒ Met Leu Ala Gly Tyr

You can learn more about translation at

brainly.com/question/16305501

brainly.com/question/25017567

#SPJ1

3 0

1 year ago

Give three examples of biomagnification ! Please help

Kaylis [27]

Answer:mercury, lead, chromium

Explanation:

8 0

3 years ago

Read 2 more answers

What role can exosomes play in disease treatment? who can tell me detailed information? Any help would be appreciated. Thanks in

jolli1 [7]

Answer:

Exosomes as Therapeutic Target

Given the fact that elevated exosome levels are often correlated with greater severity of different types of cancer, reducing circulating exosomes to normal levels is one of therapeutic strategies to increase treatment efficacy. There are different approaches to modulate exosome production: 1) Inhibition of exosome formation: inhibit crucial proteins involved in exosome formation pathway; 2) Inhibition of exosome release: inhibit important regulators of exosome release process, increased intracellular Ca2+, change cellular microenvironmental pH; 3) Inhibition of exosome uptake: add proteinase for surface proteins on exosomes may serve as receptors for uptake pathways. In addition to control exosomes production, removal of exosomes from the entire circulatory system might be a novel strategy for cancer treatment.

Exosomes could also be used as cancer immunotherapy becasue tumor-derived exosomes carry antigens that is a great source of specific stimulus for the immune response against tumors. Both tumor-derived and dendritic cell-derived exosomes have showed capability to stimulate tumor antigen-specific responses in experimental animal models and human clinical trials.

Exosomes as Targeted Drug Delivery Vehicles

Exosomes became one of the most common methods applied in drug delivery system because of several advantages they have. Firstly, exosomes normally have a small size 40-100 nm, which is more homogenous compared to other microvesicles. This will lead them to evade rapid clearance by the mononuclear phagocyte and enhances passage through fenestrations in the vessel wall. Secondly, due to their endogenous origin, they are less toxic for and better tolerated by the immune system. It facilitates them to avoid causing side effects that normally occur with synthetic nanoparticles. Additionally, the specific ligand or protein expressed on the exosome surface increases efficiency of cargo into the cytosol of the target cell, and therefore fewer off-target effects. Exosomes are generally found most useful as a drug delivery medium in cancer therapy, anti-inflammation and gene interference therapy such as transferring of miRNA.

There are different kinds of cargos encapsulated by exosomes, especially like siRNA or miRNA. The delivery of RNA is attracting because they are rapid degradation in cell circulation and have the limitation in passing through the membrane and in cellular uptake. Chemotherapeutics loaded into exosomes is also used for cancer therapy such as doxorubicin. In principle, there are four key components to achieve correct functionality and efficacy during exosomes drug delivery:1) Choosing the donor cell type to produce drug-carrying exosomes; 2) Using correspond methods to encapsulate the exosomes cargo; 3) Enhancing the specificity of cargo delivery by targeting peptides on the surface of the exosomes; 4) Administrating exosomes to target the area of disease.

Explanation:

https://www.creative-biostructure.com/exosome-applications-652.htm

5 0

2 years ago