1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Igoryamba
3 years ago
9

Chronic Myelogenous Leukemia (CML) is a type of cancer that is caused by a specific chromosomal alteration that leads to the ina

ppropriate expression of a kinase called Abl. Kinases are enzymes that put phosphate groups onto macromolecules such as proteins. A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
A) By binding to the active site, the drug decreases the activation energy for the reaction driven by Abl kinase.
B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
C) By binding to the active site, the drug allows for a better induced fit between Abl kinase and its substrate.
D) By binding to the active site, the drug increases the amount of free energy released from the reaction driven by Abl kinase.
Biology
1 answer:
Degger [83]3 years ago
4 0
<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?

</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
</span>
Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
You might be interested in
If calcium levels within a man’s blood drop too low it can result in twitching, depression, coma, or even death. Which character
kvv77 [185]
Living things must obtain homeostasis
6 0
3 years ago
Construction contributes to soil erosion because...
Mamont248 [21]

Construction contributes to soil erosion because;

C. It removes vegetation from the building site.

8 0
4 years ago
Read 2 more answers
How does the Classification system distinguish between organisms?
polet [3.4K]

Answer:

By organising them into five major kingdoms and further dividing each kingdom into phyla (or divisions), classes, orders, families, genus, and species.

Explanation:

There are five kingdoms:

  1. Monera: bacteria
  2. Protista: amoeba, paramecium, euglena
  3. Fungi: yeast, rhizopus
  4. Plantae: flowering and non-flowering plants
  5. Animalia: animals (vertebrates and invertebrates)

Organisms that share the most similar features are grouped into the same species. Species with similar features fall under the same genus. Several genus make up a family, several families make up an order, several orders make up a class, several classes make up a phylum (or division), and several phyla (or divisions) make up a kingdom.

Note: there are three domains (or superkingdoms): Archea, Bacteria, and Eukarya.

5 0
3 years ago
Root vegetables, such as carrots, are classified as what type of root system? A. Dermal Root System B. Nutritious root system C.
timurjin [86]

Answer:

C. Tap root system

Explanation:

The taproot is the primary root that is derived from the radicle directly. This primary root has many lateral roots originating from it. Root vegetables such as carrots are classified as tap roots.

These root vegetables are fleshy in nature. The taproot of carrot is modified to store the food. Storage of food makes the tap roots of these vegetable swollen in appearance. Another example of root vegetable is turnip which is also a taproot.

6 0
3 years ago
How do biological clocks use feedback and feed forward inhibition to control sleep wake cycle
Vinil7 [7]
We do a little more about how much you want to be the first to know that the government is not cycled rest he's sleep woe
4 0
3 years ago
Other questions:
  • Tay-Sachs disease is a human genetic abnormality caused by insufficient activity of a hydrolytic enzyme called hexosaminidase A.
    9·1 answer
  • What is incomplete dominance
    12·1 answer
  • What phase occurs between the full moon and the third quarter?
    10·1 answer
  • (0.2 pts) Some foods that are rich in complex carbohydrates can be difficult to digest. Gas often forms as the foods are slowly
    7·1 answer
  • Based on your results, which antibiotic is a narrow-spectrum antibiotic? neomycin, penicillin, erythromycin, ampicillin
    8·1 answer
  • The process of gamete formation during sexual reproduction is correctly represented by which illustration?
    9·2 answers
  • Please help ASAP!! This is homework meaning die tomorrow!!
    5·1 answer
  • Help if you answer in under 5min equals brainlist
    13·1 answer
  • Epigenetics is defined as the
    13·1 answer
  • Which sentiment is supported by the diagram?
    11·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!