Question

What appears to be the role of sirna in destroying the target mrna upon which it and its associated proteins act? it cleaves the target mrna. it activates the risc complex ribonuclease. it destabilizes the target mrna's binding to its associated proteins. it guides the risc that cleaves the target mrna to that target mrna due to its complementarity to that molecule. link to text link to text?

Answer 1

siRNA guides the RISC that cleaves the target mRNA. siRNA binds to its target mRNA due to its complementarity. Small interfering RNA (siRNA) has a function in RNA interference, which means it causes gene silencing through repression of transcription. siRNA together with some proteins (like Argonaute) form the RISC. When siRNA recognize the target mRNA it causes degradation of mRNA and thus silencing the gene that encodes that mRNA.