The best option from the list would be that "<span>A. Access to rivers and railroads was needed to get manufactured goods to markets," since the factories tended to be very far away from major consumer cities. </span>
Describing the struggles of the urban poor.
There were episodes of widespread famines, and also of deadly epidemics. Soil exhaustion, overpopulation, wars, diseases and climate change cause hundreds of famines in medieval Europe.<span> Around 1300, centuries of European prosperity and growth came to a halt. Famines such as </span>Great Famine of 1315–1317<span> slowly weakened the populace. Few people died of starvation because the weakest had already succumbed to a routine disease they otherwise would have survived. A plague like the </span>Black Death<span> killed its victims in one locality in a matter of days or even hours, reducing the population of some areas by half as many survivors fled.</span>