Question

Hank began snorting cocaine about three years ago. he said the first high was the most astounding, exciting, mind-blowing experience he'd ever had. however, he has never been able to recapture that initial euphoria, and now he needs more and more of cocaine to get anywhere near his first experience. hank has most likely:

Answer 1

Hank has most likely "built up a tolerance to cocaine".

Tolerance is a pharmacological idea depicting subjects' diminished response to a medication following its rehashed utilize. Expanding its dose may re-open up the medication's effects, however this may quicken tolerance, additionally lessening the medication's effects.  Like in the given example Hank has developed a tolerance for cocaine by repeated use of the drug. The procedure of tolerance development is reversible.