What signal transduction mechanism is most commonly utilized by the receptor for glucagon?
1 answer:
Plasma membrane receptors have a hormone recognition domain one or more
Trans membrane domains, and an intracellular domain that generates the intracellular signals.
Cyclic AMP is generated by adenylate cyclase and stimulates phosphorylation throughout the cell by allosteric activation of protein kinase A.
Inactivation of the active epinephrine hormone-receptor complex by phosphorylation desensitizes the receptor.
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