Nucleus, electrons are found in shells or orbitals that surround the nucleus of an atom, protons and neutrons are found in the nucleus. They group together in the center of an atom.
Answer: A compound that doesn't have carbon.
Answer: If a mutation occurred in Silencer of Death Domain (SODD) that prohibited its interaction with the DD of TNF receptor, the TNF receptor would evoke its response by binding to a transmembrane receptor, TNFR1.
Explanation: Binding to TNFR1 inhibits the recruitment of cytoplasmic signaling proteins to TNFR1 to prevent recruitment of a number of protein (TRADD) or prevent spontaneous aggregation of the cytoplasmic death domains of TNFR1 molecules.
SODD mechanism is useful in preventing unwarranted TNFR1 activation in the process of apoptosis.
Answer:
Repair mechanism for base cleavage (BER)
Explanation:
Repair by base cleavage (BER)
The altered bases are specifically recognized by glycosylases and removed, generating an AP site. The hole is filled by a DNA polymerase that takes the healthy strand as a template. This system arises not only by exposure to external agents, but also by the cell's own activity.
In case of damage in more than one nucleotide, repair by nucleotide excision (NER) is performed.
Nucleotide excision repair (NER)
The damaged area is recognized by UvrA and B, then A and B separate and UvrC enters which forms a complex with endonuclease activity with B. This enzyme cuts the T-dimer and the gap is filled by a DNA polymerase. There is also the TC-NER system (transcription-coupled nucleotide repair system). The alteration of these mechanisms gives rise to diseases such as: Xeroderma pigmentosum, Trichotiodystrophy or Cockayne Syndrome
