Answer:
The nuclear receptor superfamily comprises a large group of transcription factors that play a key regulatory role in development and homeostasis of multicellular organisms. A special feature of nuclear receptors is their ability to bind to condensed chromatin templates, which makes them important initiators of gene transcription. Moreover, the ability of nuclear receptors to sequentially recruit a variety of transcription factors and coregulators to target promoters and to orchestrate the whole process of gene transcription confirms their biological significance and stimulates intensive research and a high level of scientific interest in this field. In this review, we summarise current knowledge regarding the structure and function of nuclear receptors as principal regulators of gene expression. Emphasis is given to the molecular mechanisms of nuclear receptor-mediated transcriptional activation and repression including recent progress made in this area.
<span>When there is an imbalance
from the homeostasis of the body, a disorder or disease may result. Homeostasis establishes balance and equilibrium of the internal and
external part of the body. If this balance or ideal levels are interrupted, the
body may correct it by making all system work together or the problem may
worsen based on certain influences and may not allow normal functioning of the
organism, by either deficiency or toxicity. </span>
Moreover, some factors that influence
the body’s ability to maintain homeostatic balance are genetics, lifestyle
choices and environmental exposure.
Tiny droplets of water and ice crystals
Answer:
<h3>DNA replication is the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules. Replication is an essential process because, whenever a cell divides, the two new daughter cells must contain the same genetic information, or DNA, as the parent cell.</h3>
