The DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication and usually work in pairs to create two identical DNA strands from one original DNA molecule. During this process, DNA polymerase “reads” the existing DNA strands to create two new strands that match the existing ones.
Every time a cell divides, DNA polymerase is required to help duplicate the cell’s DNA, so that a copy of the original DNA molecule can be passed to each of the daughter cells. In this way, genetic information is transmitted from generation to generation.
Before replication can take place, an enzyme called helicase unwinds the DNA molecule from its tightly woven form. This opens up or “unzips” the double stranded DNA to give two single strands of DNA that can be used as templates for replication.
DNA polymerase adds new free nucleotides to the 3’ end of the newly-forming strand, elongating it in a 5’ to 3’ direction. However, DNA polymerase cannot begin the formation of this new chain on its own and can only add nucleotides to a pre-existing 3'-OH group. A primer is therefore needed, at which nucleotides can be added. Primers are usually composed of RNA and DNA bases and the first two bases are always RNA. These primers are made by another enzyme called primase.
Although the function of DNA polymerase is highly accurate, a mistake is made for about one in every billion base pairs copied. The DNA is therefore “proofread” by DNA polymerase after it has been copied so that misplaced base pairs can be corrected. This preserves the integrity of the original DNA strand that is passed onto the daughter cells.

A surface representation of human DNA polymerase β (Pol β), a central enzyme in the base excision repair (BER) pathway. Image Credit: niehs.nih.gov
Structure of DNA polymerase
The structure of DNA polymerase is highly conserved, meaning their catalytic subunits vary very little from one species to another, irrespective of how their domains are structured. This highly conserved structure usually indicates that the cellular functions they perform are crucial and irreplaceable and therefore require rigid maintenance to ensure their evolutionary advantage.
Answer:
Endometrosis could negatively affect the probability of gestating an embryo if they are growing inward. The affection of the fallopian tubes and the uterus could alter the implantation or even generate complications for the embryo during pregnancy.
In addition, endometriosis generates painful conditions in the abdominal area to the point that it is considered as menstrual cramps during menstruation, women who suffer from this disease suffer a lot during the menstrual cycle.
Regarding the reproductive system, those female reproductive systems that suffer from this disease are considered potentially malignant, since many malignant neoplasms are incited to appear in these foci of excessive proliferation of the endometrium.
Explanation:
Endometriosis can affect the walls of the fallopian tube and the uterus, since it occurs in the endometrium, that is why it bears that name.
The macroscopic appearance of this lesion at the histological level is a tumor nodule, since they are proliferative foci.
Tillage can release pollutants in the soil and increase erosion by the acceleration of the soil and wind speed.
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How doesTillage can increase erosion ?</h3>
Tillage can split soil structure, pace the decomposition and lack of natural matter, boom the hazard of erosion, break the habitat of useful organisms and reason compaction.
Each of those capability effects negatively effect soil fine. A soil's overall performance is immediately associated with a soil's fine or health. Since tillage breaks the soil, it disrupts soil structure, accelerating floor runoff and soil erosion. Tillage additionally reduces crop residue, which assist cushion the pressure of pounding raindrops.
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