The Great Compromise was one of the agreements made during the Constitutional Convention of 1787. States that had a greater population argued that they should have a greater representation in Congress. Smaller states demanded equal representation, as they argued that unequal representation would lead to an unfair dominance of the larger states over the country's affairs.
Roger Sherman ultimately came with the solution of a Congress with two houses. The House of Representatives would have representation proportional to the population in each state. However, the Senate would have 2 representatives per state. Regardless of their population.
The Spanish built missions so that they could convert Native Americans to Catholicism. The Spanish and Natives lived and worked in these missions. There were a set of rules, and if the Natives broke them, they would be punished.