Individuals who are heterozygous for the sickle-cell allele suffer less from the attack of malaria because a small percentage of the red blood cells are sickle-shaped. They are more resistant to malaria than individuals who have two copies of the normal haemoglobin allele. Heterozygous individuals have a better chance of surviving and reproducing in regions where malaria is prevalent since they do not fully contract the disease.
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i would have to say B or C. leaning more one C though, i hope i'm right haha. best of luck!! :D
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When directed mutagenesis which is also called reverse genetics is used, only a single mutation per genome is introduced. In contrast, the number of mutations per genome introduced by random mutagenesis is usually difficult to control. It is likely that the strain you obtained with a mutation in gene X after random mutagenesis contained an additional mutation or perhaps multiple mutations which ultimately was/were responsible for loss of virulence in your favorite pathogen.
