Question

Identify all the amino acid-specifying codons where a point mutation (a single base change) could generate a nonsense codon.

Answer 1

Answer:

Glutamic Acid (Glu): codons GAA, GAG

Glutamine (Gln): codons CAA, CAG.

Lysine (Lys): codons AAA, AAG, UCG

Serine (Ser): codons UCA, UCG

Leucine (Leu): codons UUG, UUA

Tyrosine (Tyr): codons UAC, UAU

Tryoptophan (Trp): codon UGG

Arginine (Arg): codons CGA, AGA

Glycine (Gly): codon GGA

Cysteine (Cys): codon UGU

Explanation:

Non sense codons are: UAA, UAG, UGA. Then following the genetic code (see attached file) a single base substitution in any of the codons indicated in the answer could generate a stop codon. This single base substitution might happen in the first, second or third base of the codon.