Usually they were on the opposite side of the indians, and they always had problems
The colonies had been practicing limited forms of self-government since the early ... persecution in England demanded the freedom to worship according to their faiths. ... The colonies along the eastern coast of North America were formed under ... belief that colonies existed in order to increase the mother country's wealth
For the answer to the question above, I believe that the answer is a. Productive Technology. The computers that we have now. The automation of businesses and by the productive technology we can make things easier and efficient.
I hope my answer helped you.
The answer is "their religion"
they died because they wasn't immune to it