Answer:
Delivered small RNAs can inhibit protein A production through the RNA interference (RNAi) mechanism, and thus impairs angiogenesis
Explanation:
The pregnancy-associated plasma protein-A is a protease enzyme involved in the formation of new blood vessels by increasing insulin-like growth factor I (IGF-I) bioavailability. Moreover, small RNAs (<200 nucleotides in length, generally 18 to 30 nucleotides) are non-coding RNA molecules that function in RNA silencing through the RNA interference (RNAi) pathway. Small RNAs are widely used in molecular biology laboratories because they can be delivered into specific cells in order to silence target mRNAs such as, in this case, the mRNA encoding protein A, by complementary base pairing and thereby inducing translational repression. In consequence, mRNAs complementary to delivered small RNAs are silenced through RNAi pathways, i.e., by cleavage of the target mRNA and/or mRNA destabilization.
1)First, prepares all the necessary equipment and material
<span>2Creating the pattern that desired for the shell</span>
<span>3)Creates the core of the shell by pouring the hollow spaces with meta</span>
<span>4)Creates molds for the shell by filling the corebox with sands and let them combined over time</span>
<span>5)Shake out the sand after the combination already cooled down</span>
<span>6) cast results are finished.</span>
Answer and Explanation: In enzyme kinetics, one constant describing enzyme activity is <em>Maximal Velocity</em> (Vmax). It indicates how fast an enzyme can catalyze the reaction. It is dependent on substrate concentration.
As the muscle is an organ which needs a great amount of energy, the enzyme glycogen phosphorilase is very active on the organ, compared to the liver, where glicose is stored. So, the Vmax of glycogen phosphorylase expressed in muscle is faster than when expressed in the liver, means the enzyme in muscle has a bigger concentration of substrate and therefore will reach Vmax faster, i.e. will be significantly larger.
Rodent like teeth, leg structure, better eyes